ALA is a mitochondrial fatty acid that is highly involved in energy metabolism. More recently it is known for its unique and powerful antioxidant abilities. ALA is an antioxidant that is produced in small amounts in the body and found in small amounts in meats and greens . More so in organ meats and spinach but the problem is that there hasn't been a full evaluation of ALA in foods like there has been for other nutrients. Like CoQ10,ALA production in the body drops off as we age and has become a popular supplement. ALA is unique because it is both water and fat soluble and crosses the blood-brain barrier well in its supplemental form.


When the body has optimal levels of ALA running through the system the body has a much stronger antioxidant effect and ALA is a great free radical scavenger which in turn minimizes oxidative damage. In your brain, alpha-lipoic acid boosts the production of the neurotransmitter acetylcholine. And even increases glucose uptake in brain cells. Providing you with a boost of mental energy. There has been very promising studies that show ALA can be used effectively for the treatment of diabetes and alzheimer's. Especially for diabetic nerve pain due to its strong anti-inflammatory effects. 

Alpha-Lipoic Acid helps:

Protect Neurons-ALA has a powerful ability to neutralize the damaging effects of oxidative stress. Studies show lipoic acid even reducing brain damage after a stroke.
Neurotransmitters-ALA boosts the production of acetylcholine and glucose uptake in the brain. Showing promise in preventing or managing Alzheimer’s Disease.
Brain Energy-ALA regenerates other depleted antioxidants (Vitamins C & E, glutathione), and recycles CoQ10. Reducing inflammation, and getting rid of heavy metals. Boosting cellular energy and memory. 


ALA is obviously effective in the treatment of diabetes and some neurodegenerative disorders but I use it for the boost I get in performance physically and cognitively. Due to its role in energy production and the strong antioxidant effects, it plays a  strong roll in my performance and recovery. These are just a few the benefits of using ALA;

-Powerful Antioxidant
-Boosts Acetyl Choline In The Brain
-Helps Gets Rid Of Heavy Metals In The Brain
-Promotes Muscle Regeneration After Exercise
-Decreases Inflammation
-Increases Insulin Sensitivity
-Prevents and Improves Diabetes
-Helps Combat Metabolic Syndrome
-Protects the Brain
-Reduces Risk Of Metabolic Syndrome


If you are using ALA to help treat diabetes or any neurodegenerative diseases then the dose is quite high to get the health benefits. I have seen studies that recommend as high as 600-800mg twice a day. For the purpose of performance and general health the doses usually are recommended at 20-100mg a day. ALA is recommended first thing in the morning on an empty stomach for maximum absorption. At low doses I haven't seen any side effects of using ALA. That being said, my personal experience is that a 50mg dose daily is more than adequate especially if you are eating a healthy diet full of quality organ meets and greens. I have seen reports of stomach issues and even insomnia for doses above 100mg a day. My last tip for ALA use is to stack it with CoQ10 and Acetyl L-Carnitine for the energy benefits.


Alpha Lipoic Acid is proven to be a strong antioxidant that fights free radical damage. It is essential in energy production and is a powerful tool in fighting neurological decline. Another  great tool for the toolbox. 



Ares NikolopoulosComment